

Karl Popper introduced a concept of falsifiability as a criterion and process of solid scientific process but the process of hypothesis and concept generation do not have particular logic behind it 1. Since scientific research has been one of the most important activities that drove our civilization forward, the implications of such development will be profound.Īttempts to understand the process of scientific discoveries have a long tradition in the philosophy of science as well as artificial intelligence.

Building the machine to make it happen could be one of the most important contribution to society, and it will transform many areas of science and technology including systems biology. Understanding, reformulating, and accelerating the process of scientific discovery is critical in solving problems we are facing and exploring the future. Nobel Turing Challenge as an ultimate grand challenge The Nobel Turing Challenge aims to develop a highly autonomous AI system that can perform top-level science, indistinguishable from the quality of that performed by the best human scientists, where some of the discoveries may be worthy of Nobel Prize level recognition and beyond. It could give rise to a human-AI hybrid form of science that shall bring systems biology and other sciences into the next stage. It may be an alternative form of science that will break the limitation of current scientific practice largely hampered by human cognitive limitation and sociological constraints. At the same time, what may be implemented by “AI Scientists” may not resemble the scientific process conducted by human scientist. In other words, the “science of science” needs to be established, and has to be implemented using artificial intelligence (AI) systems to be practically executable. This requires an in-depth understanding of not only the subject areas but also the nature of scientific discoveries themselves. Accelerating the speed of scientific discovery is therefore one of the most important endeavors. It uncovered the principles of the world we live in, and enabled us to invent new technologies reshaping our society, cure diseases, explore unknown new frontiers, and hopefully lead us to build a sustainable society. Scientific discovery has long been one of the central driving forces in our civilization.
